High blood pressure could contribute to Alzheimer’s

A new study suggests that there may be an association between increased blood pressure and Alzheimer’s disease.

The study was conducted on the basis of previous findings on the brain remover system by Maiken Nedergaard, co-director of the US Neuromedicine Center. The previous work showed how cerebrospinal fluid pumped into the brain led to the elimination of residues. Research also shows that the glimpse of waste disposal is more active when we sleep and can be degraded by strokes or traumas, writes.

Recent research shows in detail how the functions of the glial system in the perivascular spaces surround the arteries in the outer membrane of the brain. Thus, Humberto Mestre, a doctoral student at Nedergaard’s laboratory, injected particles into the cerebrospinal fluid of the mice and then used two photon microscopes to create the videos showing the particle movement through the perivascular spaces.

By analyzing the video, specialists have been able to get more information about the activity during this stream. Specialists have found that cerebrospinal fluid is synchronized with heartbeat. Also, when high blood pressure was induced in mice, the flow slowed down, not being as effective. So the artery walls must contract harder to keep their shape.

“This is extremely important because the early onset of blood pressure is considered a risk factor for Alzheimer’s in humans,” said Douglas Kelley, Fluid Dynamics Specialist.

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